Lead Sponsor

Inonu University

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

•Patients diagnosed with periodontitis.
•Systemically healthy individuals.
•Patients aged between 18 and 65 years.
•Presence of at least 20 natural teeth.
•Volunteering to participate in the study and signing the informed consent form.

•Presence of any systemic disease that may affect periodontal health or systemic inflammatory response (e.g., Diabetes Mellitus, immunological disorders).
•Current smokers or use of any tobacco products.
•Pregnancy or lactation.
•Use of systemic antibiotics, anti-inflammatory drugs, or immunosuppressive medications within the last 6 months.
•Having received any non-surgical or surgical periodontal treatment within the last 6 months.
•Known allergy or sensitivity to chlorhexidine or Morus nigra (blackberry) extracts.
•Patients using orthodontic appliances.