Age

40–80

Sex

ALL

Healthy volunteers

Not accepted

Age 40-80 years
Mild-to-moderate knee OA as determined by radiographs demonstrating Kellgren- Lawrence grade 2-3
Self-reported pain of at least 5/10 VAS questionnaire
Failure of conservative therapy, such as pain medications, for at least 3 months
Patient must understand and sign the informed consent
Patient can comply with the proposed follow-up schedule
Patient can follow the post-operative management

History of rheumatoid arthritis
Renal insufficiency precluding angiography (GFR \< 50 mL/min)
Irreversible coagulopathy
Previous knee arthroplasty on the intended knee
Existing knee joint infection
Kellgren-Lawrence grade 1 or 4
Severe atherosclerosis as manifest by claudication and/or diminished peripheral pulses
Life expectancy \< 6 months
Infectious arthritis
Allergy to iodinated contrast resulting in anaphylaxis
Pregnant or interested in becoming pregnant three months from the date of the GAE procedure
Involved in litigation or worker's compensation claims

Genicular Artery Embolization for Knee Osteoarthritis