Yin Yao

CONTACT

Lead Sponsor

Tongji Hospital

Age

3 - 12 years

Sex

ALL

Healthy Volunteers

No

•\- 3-12 years
•1. Children with physician-diagnosed allergic rhinitis and typical symptoms (nasal obstruction, watery rhinorrhea, paroxysmal sneezing);
•2. Co-existing adenoidal and tonsillar hypertrophy meeting surgical indications;
•3. No systemic or topical corticosteroids, leukotriene antagonists, or antihistamines within the past 3 months.

•1. Prior adenoidectomy, tonsillectomy, or radio-frequency ablation;
•2. Nasal polyps, cystic fibrosis, primary ciliary dyskinesia, fungal rhinosinusitis, systemic vasculitis/granulomatosis, tumor, or immunodeficiency;
•3. Endoscopic nasal surgery within 6 months or severe asthma precluding surgery;
•4. Upper respiratory infection within 4 weeks;
•5. Serious metabolic, cardiovascular, immune, neurologic, hematologic, gastrointestinal, cerebrovascular, or respiratory disease, or any condition judged by the investigator to interfere with outcome assessment or participant safety;
•6. Currently enrolled or within 30 days of participation in another clinical trial.