Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shanghai Zhongshan Hospital
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 18 years and ≤ 75 years, regardless of sex.
Histopathologically confirmed mucosal melanoma.
Focal, lymph node metastatic, or oligometastatic mucosal melanoma assessed as completely resectable by multidisciplinary team (surgery/ENT/gynecology/colorectal, radiotherapy, oncology, imaging/pathology, etc.).
ECOG Performance Status of 0 or 1.
Life expectancy ≥ 12 weeks.
You may not be if
Prior treatment with PD-1/PD-L1 antibodies or anti-angiogenic agents.
Ocular melanoma or melanoma of unknown primary site.
History of immunodeficiency, acquired or congenital immune deficiency diseases, or organ transplantation.
Pregnant or breastfeeding women.
Abnormal coagulation function (APTT \> 43 seconds or INR \> 1.5 × ULN), or history of bleeding tendency or bleeding events (e.g., gastrointestinal bleeding, gastric ulcer bleeding) within 3 months before enrollment.
Clareo Health | Neoadjuvant SHR-1701 Plus Famitinib With Response-guided Adjuvant Therapy in Resectable Mucosal Melanoma
