Individuals with oral dysesthesia (worst VAS sensitivity/burning score ≥ 7 over the last week)
Ability to understand and the willingness to sign a written informed consent document
You may not be if
Inability to comply with study instructions
Uncontrolled intercurrent illness or psychiatric illness/social situations that would limit compliance with study requirements\*
Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the participant or the quality of the data.
Advanced kidney disease
Patients receiving antineoplastic therapy \[e.g., tyrosine kinase inhibitors (TKIs), radiation\] that could increase the risk of oral dysesthesia
Known altered mental status, encephalopathy, or cognition impairment
Ataxia
Known alcohol use disorder
Concomitant opioid therapy
Diagnosis of oral cancer currently undergoing therapy
Already using topical therapy for mouth pain (e.g., lidocaine, Magic mouthwash)\*
Any opioid pain medication\*
Treatment with another investigational drug or other intervention within 2 weeks. Patients will be recommended to stop previous medication for 2 weeks before starting the study treatment.
(asterisk) \*Modifiable criteria, with a timeframe of 2 weeks for a washout period.
