Second Affiliated Hospital, Zhejiang University, School of Medicine
Age
50–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Meet the diagnostic criteria for AD-derived MCI or early AD \[Clinical rating: CDR 0.5 (MCI) / 1.0 (mild AD), i.e., clinical stage 3-5; PIB-PET positive for pathology\]
Male or female
50-85 years old
Not currently participating in other research studies
Volunteers must provide written informed consent prior to study participation and voluntarily sign the informed consent form
Volunteers are able to communicate effectively with investigators and comply with study procedures to complete the study
You may not be if
Other neurological disorders: e.g., vascular dementia, dementia with Lewy bodies, frontotemporal lobar degeneration, prion diseases, etc.
Systemic diseases or metabolic disorders: e.g., hypothyroidism, vitamin B12 deficiency, hepatic and renal failure.
Infectious diseases: e.g., neurosyphilis, HIV-associated encephalopathy, and other infectious diseases.
Psychiatric disorders: cognitive symptoms caused by severe depression (pseudodementia), schizophrenia, etc.
Effects of drugs/toxins: long-term use of benzodiazepines, anticholinergic drugs, or alcohol dependence.
