Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University Medical Center
With
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients presenting to the emergency department with left-sided uncomplicated diverticulitis
Radiologic score (moderate diverticulitis per Ambrosetti classification)
Age 18-90
Access to a smartphone with internet access.
You may not be if
Complicated diverticulitis (abscess, free air, peritonitis)- severe diverticulitis by Ambrosetti classification
Diverticulitis other than left colon
Contraindication to use of study medication (ie advanced renal failure or allergy to all antibiotics used in the study)
Concurrent cancer diagnosis
Concurrent IBD Diagnosis
Any other disease process with life expectancy \< 6 months
Concurrent chronic pain diagnosis.
Women in pregnancy or breastfeeding
Antibiotic treatment for any reason in the last 3 weeks
Diagnosis of prior episode of acute diverticulitis in the past 3 months
Significant comorbidities: diabetes mellitus with organic involvement (retinopathy, angiopathy, nephropathy), emergency assistance for a cardiogenic event in the last 3 months (acute myocardial infarction, angina, heart failure), decompensation of chronic liver disease in the last 3 months (Child ≥ B) and end-stage renal disease.
Immunodepression: the absence, and immunodepression is the presence, of any of the following: active neoplastic disease, hematologic malignancy, human immunodeficiency virus long-term corticosteroid treatment, immunosuppressant therapy (20mg pred (or equivalent) for \>2 weeks), transplant, splenectomy and genetic immunodeficiency
Previous colectomy
Patients with dementia, memory disorders or other cognitive impairment that would impact their ability to provide informed consent or otherwise participate in the trial
