Wide-Angle Tomosynthesis and AI in Diagnostic Mammography

This prospective observational study evaluates the use of wide-angle digital breast tomosynthesis (DBT) and an artificial intelligence (AI) decision-support tool (Transpara) during diagnostic mammography at The Ottawa Hospital. All imaging performed in the study is part of routine clinical care and uses the Siemens MAMMOMAT B.brilliant system. The first 700 patients will have images interpreted without AI, and the next 700 with AI available to the radiologist. No additional imaging or procedures are required beyond standard care. The study will compare diagnostic confidence, need for supplementary imaging, biopsy outcomes, and overall workflow efficiency between the AI-supported and non-AI groups. Clinical follow-up for up to two years will be used to assess diagnostic accuracy and cancer outcomes.