1. Confirmed diagnosis of cirrhotic portal hypertension.
2. Endoscopic examination confirmed the presence of severe esophagogastric varices accompanied by acute bleeding. Rebleeding occurred after endoscopic variceal ligation (EVL) treatment..
3. Presence of hypersplenism causing significant thrombocytopenia and/or leukopenia.
4. Liver function Child-Pugh class A or B (score 7-9).
5. Age 18-75 years.
6. Patient provides written informed consent.
You may not be if
1. Liver function Child-Pugh class C (score ≥10), or Model for End-Stage Liver Disease (MELD) score \>18.
2. Severe right heart failure or pulmonary hypertension.
3. Uncontrolled systemic infection or sepsis.
4. Polycystic liver disease, portal cavernous transformation, or portal vein thrombosis (affecting procedure or shunt creation).
5. Advanced hepatocellular carcinoma (beyond Milan criteria) or other uncontrolled malignancies.
6. Severe hepatic encephalopathy (West-Haven grade III-IV) unresponsive to medication.
7. Severe contrast agent allergy (affecting TIPS procedure).
8. Pregnancy or lactation.
9. Any severe non-hepatic disease with a life expectancy \<1 year.
10. Recent gastric and duodenal ulcers.
11. Inability to comply with follow-up or provide informed consent.
Clareo Health | Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism
