Finding studies
Finding studies
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CONTACT
Lead
Roswell Park Cancer Institute
With
PRIMARY OBJECTIVE: * To evaluate the safety and tolerability of GB-5267 in patient with platinum resistant ovarian cancer * To determine the maximum tolerated dose (MTD). SECONDARY OBJECTIVE: \- To assess the anti-tumor activity of GB-5267 This is a dose escalation study of GB-5267 In Cohort 1 Patients receive IV only infusion. Dose escalation continues until Maximum tolerated dose (MTD) is established. Once the MTD has been established Cohort B (Dose expansion with Combined IV and IP Infusion) is intended to assess whether this approach enhances local antitumor effects in the peritoneal cavity.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted