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Not Yet RecruitingNANCT07487454

Sham-Controlled Rapid-Acting Neuromodulation for Depression

The goal of this study is to learn whether 5 days of accelerated intermittent theta burst stimulation (iTBS), a rapid form of transcranial magnetic stimulation (TMS), which is a non-invasive procedure...

Lead sponsor: University of California, Davis•1 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Manpreet K Singh, MD, MS

CONTACT

916-734-2011 mpksingh@health.ucdavis.edu

Sponsors

Lead Sponsor

University of California, Davis

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•English speaking
•Able to provide informed consent
•18-65 years old
•Meets MDD criteria per the Mini International Neuropsychiatric Interview (MINI)

Exclusion Criteria

•Unable to consent (due to medical condition, acute psychosis, substance use, etc)
•Use of benzodiazepines or medications that would interfere with TMS treatment as per PI discretion
•Active substance use or severe substance use that in the opinion of the PI would interfere with study participation
•Untreated, active psychosis
•Female patient who is breastfeeding, pregnant or who is planning a pregnancy during the study
•Contraindications to receiving TMS and/or MRI as determined by screening questionnaires
•Participation in any clinical study with exposure to any investigational treatment or product within the previous 30 days, or plan on concurrent participation in other studies.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 16, 2026Terms

Trial snapshot

StatusNOT_YET_RECRUITING

PhaseNA

Enrollment264

Start dateDec 2026

Last updatedJun 16, 2026

Condition

Depression - Major Depressive Disorder

Locations shown

UC Davis Medical Center

Sacramento, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 16, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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