Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Chinese University of Hong Kong
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
≥18 years old
without severe deformity in MCPJ
with active disease, which is defined as ≥1 tender joints and ≥1 swollen joints, despite previous treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) for ≥ 4 weeks
with at least one poor prognostic factor (eg, polyarthritis, structural damage on HR-pQCT or CR, elevated acute phase reactants, dactylitis, nail involvement or HAQ-DI\>1)
symptom duration ≤ 2 years
You may not be if
on csDMARDs unless being prescribed for skin psoriasis (e.g. cyclosporin)
limited in ability to perform usual self-care, vocational, and avocational activities
pregnancy
previous therapy with b/tsDMARDs
predominant active axial PsA or significant uveitis/inflammatory bowel disease requiring immediate b/tsDMARDs therapy
the presence of active inflammatory diseases other than PsA
active infection in 2 weeks before randomization or a history of ongoing, chronic, or recurrent infections including tuberculosis
history of malignant disease within the past 5 years (excluding basal cell carcinoma or actinic keratosis, in-situ cervical cancer, or non-invasive malignant colon polyps)
contraindications to MTX or adalimumab
Clareo Health | Preventing Structural Damage in Early Psoriatic Arthritis