A Double Blind, Placebo Controlled 6-week Pre-operative Randomised Clinical Trial of a Microbiome Modulator "WellBiome" Versus Placebo on Cardiac Surgical Outcomes and NHS Cost Savings.

Exclusion Criteria

• •Active cancer
• •Any gastro-intestinal surgery or currently under the care of the GI clinical team for any clinically significant digestive issue (Crohn's, IBS, ulcerative colitis).
• •On or had antibiotic treatment in the last 3 months.
• •Patients who have taken ibuprofen in the last week or any condition that increases the likelihood of regular or sustained use during the intervention.
• •On proton pump inhibitors (Omeprazole, Esomeprazole, Lansoprazole, Rabeprazole, Pantoprazole) within the last one month on long acting non-steroidal anti-inflammatory drugs in the last month or any condition that increases the likelihood of regular use during the intervention.
• •Taking any prebiotic or probiotic supplementation within the last three months
• •Patients who are vegetarians or vegans