Exergaming for Improving Upper Limb Functions in Parkinson's Disease

Upper limb motor impairments in Parkinson's Disease significantly affect daily functioning and independence . While digital exergaming has emerged as a promising tool in neurorehabilitation, traditional models often rely solely on screen-based interaction and lack real-world physical engagement. Recent studies have highlighted the need to include tactile and sensory feedback to improve functional relevance and user experience. Integrating physical objects into exergames referred to as a "phygital" approach, enhances realism, encourages multisensory stimulation, and may result in better motor learning and functional outcomes. After the selection of subjects as per the guideline of university ethical review board. Informed consent will be taken from each participant. Participants who meet the inclusion criteria and provide informed consent will be assigned to one of two groups (30 per group) Data collection will occur in private examination rooms to ensure privacy and minimize distractions during assessments. Measures will be taken to maintain participant privacy during assessments and data collection. Data will be collected using Box and Block Test (BBT). The intervention group (phygital) will receive 36 sessions (three sessions per week over 12 weeks), each lasting approximately 30 minutes, involving structured exergaming tasks using physical objects (e.g., blocks, spoons, cups) combined with digital prompts on a tablet or laptop. Control group B will receive the same session frequency and duration, with identical digital prompts, but without the use of physical objects. While conventional Physical Therapy will be given to all the subjects of both groups. All sessions will be conducted under the supervision of a physiotherapist in a controlled clinical environment. Data will be collected at two points: baseline (pre-intervention), immediately after the 6-weeks intervention. Outcome measures will include the Box and Block Test (BBT) for gross manual dexterity. Data shall be collected through an assessor who will be blinded to the patient group to minimize biases. Data will be analyzed using IBM SPSS version 25. Descriptive Statistics shall be used to summarize demographics and clinical characteristics (e.g., age, gender, P.D. stage) and shall be presented as means, standard deviations, frequencies, and percentages. Data will be visualized using bar charts and tables. Within group comparisons will be performed to assess pre- and post-intervention changes using the paired t-test for data that meet assumptions of normality. If the data are non-normally distributed, the Wilcoxon signed-rank test will be used as a non-parametric alternative. For between-group comparisons, the independent t-test will be applied to compare outcomes between the intervention and control groups when data are normally distributed, while the Mann-Whitney U test will be used for non-parametric data. Independent sample t test will be used for comparison of hand motor movements between. A p-value ≤ 0.05 will be considered as significant.