A Study Comparing Safety and Efficacy of SHR-3167 Fixed-Dose Titration and Individualized-Dose Titration in Adults With Type 2 Diabetes Inadequately Controlled With Oral Antihyperglycemic Agents

Exclusion Criteria

• •1. Uncontrollable hypertension: systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg at screening.
• •2. Diagnosed or suspected with type 1 diabetes mellitus, latent autoimmune diabetes mellitus in adult (LADA), other special types of diabetes or secondary diabetes.
• •3. Known or suspected allergy or intolerance to the test drug or excipient.
• •4. There was a history of diabetic ketoacidosis or hyperglycemic hyperosmolar state within the previous 6 months.
• •5. There is acute or chronic hepatitis, liver cirrhosis, or a history of other serious liver diseases.
• •6. Malignancy within 5 years prior to screening or high risk of recurrence.
• •7. Those who have a history of severe cardiovascular and cerebrovascular diseases within 6 months before screening.
• •8. Participated in clinical trials of any drug or medical device within 3 months prior to screening.