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High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea: Study Protocol for a Prospective Nonconcurrent Multiple-Baseline Single-Case Experimental Design With Stability-Based Phase Transition
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Santa Catarina State University - CEFID (Center of Health and Sport Sciences)
Florianópolis, Santa Catarina, Brazil
Start Date
May 1, 2026
Primary Completion Date
May 1, 2027
Completion Date
December 1, 2027
Last Updated
March 13, 2026
10
ESTIMATED participants
High-Intensity Progressive Inspiratory Muscle Training (IMT)
DEVICE
Lead Sponsor
University of the State of Santa Catarina
NCT07446634
NCT07191314
NCT05497180
Data Source & Attribution
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