Impact of Date Consumption on Metabolic Control and Oxidative Stress in Patients With Type 2 Diabetes

Inclusion Criteria

• •Age 18-65 years
• •Type 2 diabetes diagnosed for at least one year
• •Well-controlled diabetes on oral antidiabetic drugs for at least 3 months, with a target baseline HbA1c \< 8%
• •Duration of diabetes \< 15 years
• •Patient available for an 8-week period
• •Written informed consent
• •Patients on insulin therapy
• •Oral antidiabetic treatment modified within the 3 months prior to inclusion
• •Diabetes with established microvascular or macrovascular complications
• •Severe intercurrent diseases (severe renal insufficiency, severe liver disease, cardiovascular history, neoplasia, inflammatory disease)
• •Pregnancy or breastfeeding
• •Known allergy or intolerance to dates
• •Dietary regimens incompatible with isocaloric substitution (e.g., strict ketogenic diet, prolonged fasting)
• •Inability to understand or comply with study instructions (cognitive impairment, language barrier without interpreter, major logistical constraints)