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Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate | Clinical Trials | Clareo Health

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Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate

Impact of Daily Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate :A Randomized , Single Blinded ,Controlled Trial"

NCT07466030•Assiut University

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate the impact of daily tadalafil 5 mg on storage lower urinary tract symptoms (LUTS) during the early postoperative period following Anatomical endoscopic enucleation of prostate in a randomized controlled clinical trial.

Eligibility

Age

All ages

Sex

MALE

Healthy Volunteers

Inclusion Criteria

•Must be able to swallow tablets
•Adult males undergoing elective AEEP for symptomatic benign prostatic hyperplasia (BPH) with prostate volume ≥40 ml , Moderate to severe LUTS defined by International Prostate Symptom Score (IPSS) ≥19 at baseline.
•Patient is Willing to participate and able to provide written informed consent

Exclusion Criteria

•Contraindications to tadalafil (e.g., nitrate use, severe hepatic/renal impairment, uncontrolled hypotension) , neurogenic bladder. , Preoperative urinary catheter dependence , post-void residual urine \>350 ml. ,, Cognitive impairment precluding questionnaire completion

Key Dates

Start Date

March 1, 2026

Primary Completion Date

March 1, 2028

Completion Date

September 1, 2028

Last Updated

March 12, 2026

Enrollment

ESTIMATED participants

Conditions

BPH (Benign Prostatic Hyperplasia)

Interventions

Tadalafil 5mg (Male)

DRUG

Omiga 3

DRUG

Contacts

Ali adel Mansour Hageb, GP

CONTACT

+201109049717 Alihajeb42@gmail.com

Adel Kurkar Abdallah, Prof Dr

CONTACT

+201098197880 kurkar1970@gmail.com

RT-310 Safety and Feasibility BPH Study

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BPH (Benign Prostatic Hyperplasia)

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ACTIVE_NOT_RECRUITINGPHASE1

RT-310 Dose Escalation BPH Study

NCT06136819

BPH (Benign Prostatic Hyperplasia)Lower Urinary Tract Symptoms

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ACTIVE_NOT_RECRUITINGNA

Safety and Effectiveness Study of the Zenflow Spring System

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 12, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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