STABLE Pilates for Hypermobility

Pilates for Hypermobility: A Pilot Feasibility Study

NCT07464093•Brigham and Women's Hospital

View on ClinicalTrials.gov

Summary

This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.

Detailed Description

In this study, investigators are looking at whether 6 weeks of Pilates-based exercise led by a licensed physical therapist can help with hypermobility-related symptoms, like pain. Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•≥ 18 years old;
•Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
•Self-reported persistent pain ≥ 3 months;
•A minimum of 3/10 self-reported pain intensity in the past week
•Able to get on and off the floor without assistance;
•Able to communicate fluently in English; and
•Able to provide written, informed consent

Exclusion Criteria

•Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
•Recent surgery or acute bone, joint or nerve injury (\<6 months);
•Have a history of a severe or progressive neurological or movement disorder;
•Pregnant, planning to become pregnant during the study, or currently breast feeding;
•Unable to get on and off the floor without assistance;
•Unable to complete study procedures due to cognitive impairment;
•Unable to provide written, informed consent; or
•Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

Locations (1)

Brigham and Women's Hospital

Chestnut Hill, Massachusetts, United States

Key Dates

Start Date

March 1, 2026

Primary Completion Date

December 1, 2026

Completion Date

December 1, 2027

Last Updated

March 11, 2026

Enrollment

100

ESTIMATED participants

Conditions

Ehlers-Danlos Syndrome (EDS)Hypermobile EDS (hEDS)Hypermobile Spectrum Disorder

Interventions

Pilates

BEHAVIORAL

Education

BEHAVIORAL

Contacts

Stephanie Voss, PhD

CONTACT

6177329181 svoss2@bwh.harvard.edu

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Ehlers-Danlos Syndrome (EDS)

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 11, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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