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Probiotic Improve Constipation | Clinical Trials | Clareo Health

RECRUITINGNA

Probiotic Improve Constipation

Safety and Efficacy of Lactobacillus Plantarum in Improving Constipation: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

NCT07462481•Wecare Probiotics Co., Ltd.

View on ClinicalTrials.gov

Summary

To evaluate the efficacy and safety of probiotic as a food supplement in regulating bowel habits in patients with chronic constipation, and to compare it with placebo.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•(1) Age 18-65 years; (2) Constipated patients (less than 3 bowel movements per week and/or Bristol Scale type 1 and 2); (3) Able to complete the study according to the trial protocol; (4) Patients who have signed the informed consent form; (5) Study participants (including male study participants) have no plans to have children within 14 days prior to screening and within 6 months after the end of the trial and voluntarily use effective contraception.
•\-

Exclusion Criteria

•1. Those who have taken a substance with a similar function to the test subject in a short period of time, affecting their judgment of the results;
•2. Patients who changed their diet during the study;
•3. Patients with severe allergies and immunodeficiency;
•4. Pregnant, breastfeeding, or women planning to become pregnant;
•5. Those with severe diseases of vital organs such as the cardiovascular system, lungs, liver, and kidneys, diabetes, thyroid disease, severe metabolic diseases, malignant tumors, or severe immune system diseases;
•6. Those who have used antibiotics in the past two weeks;
•7. Those with severe psychological or mental illnesses;
•8. Those who did not consume the test sample as required or did not follow up on time, resulting in the inability to determine the efficacy;
•9. Other study participants deemed unsuitable by the researchers. -

Locations (1)

Suzhou Ninth People's Hospital

Suzhou, Jiangsu, China

Key Dates

Start Date

April 1, 2026

Primary Completion Date

June 1, 2026

Completion Date

August 1, 2026

Last Updated

March 10, 2026

Enrollment

ESTIMATED participants

Conditions

Constipation

Interventions

Probiotic

DIETARY_SUPPLEMENT

Placebo

DIETARY_SUPPLEMENT

Contacts

Ying Jin

CONTACT

18336086291 1959643812@qq.com

Optimization of taVNS Intervention Strategies for Refractory Constipation

NCT07344402

Refractory Constipation

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RECRUITING

Naldemedine in Clinical Practice in Cancer Patients With Opioid Induced CONstipation: Clinical Outcomes and Patient Experience

NCT07231796

CancerOpioid Induced Constipation (OIC)

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RECRUITING

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 10, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Probiotic Improve Constipation

Inclusion Criteria

Exclusion Criteria

Optimization of taVNS Intervention Strategies for Refractory Constipation

Naldemedine in Clinical Practice in Cancer Patients With Opioid Induced CONstipation: Clinical Outcomes and Patient Experience

A Study of Herbal Supplements in Cancer Survivors With Constipation

Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women

Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial

Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated Patients