PRIAPUS-PCa Study: Stereotactic Body Radiation Therapy (SBRT) and Androgen Deprivation Therapy (ADT) Impact on Sexual Function on Men With Unfavorable Intermediate Risk Prostate Cancer

Exclusion Criteria

• •Prior pelvic radiotherapy, prostate surgery, ADT, or chemotherapy
• •Pre-existing severe sexual dysfunction (IIEF-5 score \< 12 or pre-selection erection status score of 0: no erection)
• •Hypogonadism at presentation (baseline testosterone below normal range)
• •Contraindications to SBRT or ADT
• •Metastatic disease, second malignancy, or previous malignancies.
• •Benign or malignant penile diseases.
• •Use of medications altering ejaculation (e.g., 5-alpha reductase inhibitors)
• •Psychiatric conditions affecting questionnaire completion or QoL assessment
• •Severe comorbidities affecting QoL assessments (e.g., advanced cardiovascular disease).