Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1

Inclusion Criteria

• •1. Willing and able to give voluntary written informed consent;
• •2. Able to read and write, able to communicate effectively with the investigator, and comply with all study requirements, restrictions, and directions of the research staff;
• •3. Male or female, aged 18 to 60, at screening;
• •4. In good general health as evidenced by medical history, physical examination, ECG, serum/urine biochemistry, hematology, and serology tests;
• •5. Females of childbearing potential, and male subjects, must be willing to practice birth control for the duration of the study (unless medical documentation is provided confirming subject is permanently sterile).
• •Exclusion:
• •1. Less than 18 years of age;
• •2. Pregnant or breastfeeding;
• •3. Any significant systemic illness or unstable medical condition;
• •4. Pre-existing medical conditions or claustrophobic reactions;
• +2 more criteria