Menstrual Status, Anesthetic Consumption, and PONV

Exclusion Criteria

• •Age outside the specified range (younger than 18 or older than 65 years)
• •Male patients
• •American Society of Anesthesiologists (ASA) physical status ≥ IV
• •Severe systemic comorbidities (e.g., significant cardiovascular, hepatic, renal, or pulmonary disease)
• •Conversion from laparoscopic to open cholecystectomy
• •History of alcohol, drug, or substance abuse
• •Visual or hearing impairment interfering with study assessments
• •Current hormone replacement therapy
• •Use of oral contraceptives
• •Preoperative nausea or vomiting
• •History of severe postoperative nausea and vomiting
• •Neurological or psychiatric disorders affecting assessment reliability
• •Hemodynamic instability during surgery
• •Postoperative admission to intensive care unit
• •Acute cholecystitis at the time of surgery
• •Refusal to participate or inability to provide informed consent