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COMPLETEDPhase 4NCT07451678

Treatment of Blepharitis Induced by Demodex Folliculorum Through Eyelid Cleansing With Wipes Containing Topical Chlorhexidine

This study employed an experimental, prospective, longitudinal, before-and-after design to evaluate the efficacy of topical chlorhexidine wipes in treating blepharitis. The investigation focused on a...

Lead sponsor: Instituto de Oftalmología Fundación Conde de Valenciana•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Instituto de Oftalmología Fundación Conde de Valenciana

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age ≥ 18 years
•Clinical diagnosis of Demodex folliculorum blepharitis
•Presence of eyelash collarettes on slit-lamp examination
•Positive identification of Demodex folliculorum by epilation of 4 upper and 4 lower eyelashes per eyelid and visualization under light microscopy
•Willingness to use chlorhexidine eyelid wipes as instructed for 8 weeks

Exclusion Criteria

•Use of topical or systemic antiparasitic treatment within the past 6 weeks
•Use of topical ophthalmic antibiotics or anti-inflammatory medication within the past 6 weeks
•Known allergy or hypersensitivity to chlorhexidine
•Pregnancy or breastfeeding

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 6, 2026Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment106

Start dateJul 2024

Last updatedMar 6, 2026

Condition

Locations shown

Instituto de Oftalmologia F.A.P. Conde de Valenciana, I.A.P.

Mexico City, Mexico City

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 6, 2026Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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