Institut National de la Santé Et de la Recherche Médicale, France
Age
18–30
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
All groups:
Age between 18 and 30 years
Normal or corrected-to-normal visual acuity
Affiliated with or dependent on a social security health insurance plan
Provided informed consent and co-signed the study consent form with the investigator
Proficient in French
Control group (TEM) specific criteria:
No current psychiatric disorder (DSM-IV Axis I), except anxiety disorders
No lifetime history of (hypo)manic episodes or psychotic disorders
No first-degree family history of schizophrenia spectrum disorders
No regular use (more than one month continuously) in the past 6 months of the following medications: benzodiazepines, hypnotics, antidepressants, antipsychotics, mood stabilizers, or psychostimulants
Clinical High-Risk (CHR) group specific criteria:
Meet CHR criteria according to CAARMS: Attenuated positive symptoms (APS) below clinical threshold in intensity or frequency OR Brief Limited Intermittent Psychotic Symptoms (SPLI) OR Genetic Risk
First-Episode Psychosis (PEP) group specific criteria:
Meet PEP criteria according to CAARMS (psychosis threshold reached)
You may not be if
Pregnant, postpartum, or breastfeeding women
Individuals deprived of liberty by judicial or administrative decision
Individuals in a life-threatening emergency
Adults under legal protection measures
Adults unable to provide consent and not under legal protection
Impairment that makes participation in the study or understanding of information difficult or impossible
Alcohol dependence (AUDIT score ≥12 for men, ≥11 for women)
Current substance use disorder (DAST score \>6)
Cannabis use disorder (CUDIT-R score ≥13)
History of neurological disorders, including progressive neurological disease
Progressive retinal disease
Chronic glaucoma
Ophthalmologic conditions affecting visual acuity
Current eye infection
Hearing disorders affecting auditory acuity
Criteria incompatible with the electroretinographic device:
Presence of photosensitive epilepsy
Allergy to components of the electrode gel
Behavioral problems causing extreme agitation or aggression
Eye or surrounding tissue lesions that may come into contact with the device
Clareo Health | Perception and Integration of Sensory Information in the Early Stages of Psychosis
