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Usefulness of High-flow Oxygen Therapy to Improve the Safety of Patients at Risk of Hypoxemia Undergoing Digestive Endoscopy Under Deep Sedation: a Randomized Multicenter Comparative Study
The study investigates the use of high-flow oxygen therapy devices in patients at higher risk of complications during sedated digestive endoscopies. Sedation controlled by the endoscopist improves patient tolerance and facilitates higher-quality procedures, but it can have side effects such as hypoxemia or respiratory depression, especially in patients with sleep apnea, obesity, lung diseases, those over 60 years old, or with a history of sedation complications. While preventive measures, such as oxygen administration, are taken, the study aims to compare the effectiveness of new high-flow oxygen therapy devices with conventional nasal cannulas to improve safety during endoscopies.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Hospital Universitario Río Hortega
Valladolid, Valladolid, Spain
Start Date
March 1, 2026
Primary Completion Date
October 1, 2026
Completion Date
October 1, 2026
Last Updated
February 27, 2026
326
ESTIMATED participants
High-flow medical oxygen insufflation
DRUG
Low-flow medical oxygen insufflation
DRUG
Lead Sponsor
Outcomes'10
Data Source & Attribution
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