Active alcoholism (defined as daily use of more than 1 liter of wine and /or 3 or more shots of hard liquor) or drug abuse (defined as daily use of illicit drugs)
Severe chronic pain condition that requires daily preoperative opioid dependence
Other concomitant surgery being performed in addition to TKA
Patients undergoing bilateral TKA
Patients undergoing knee replacement revision
Patients with limited mobility (in a wheelchair or requiring a walker)
Patients who are not returning home after surgery
Clareo Health | NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty