Comparison of Iliac Crest Marrow vs. Proximal Tibia Avitus® Bone Graft

Exclusion Criteria

• •Patient is 70 yrs of age or older.
• •Patient is unwilling or unable to give consent or comply with study protocol.
• •Patient has any condition, which in the judgement of the Investigator, places the patient at undue risk or interferes with the study.
• •Patient has mental or neurological disorder that will not allow for proper informed consent.
• •Patient is known to be pregnant or breastfeeding.
• •Patient is a vulnerable subject (prisoner, mentally incompetent or unable to understand what participation to the study entails, a known alcohol or drug abuser, and/or anticipated to be non-compliant).
• •Patient has any condition, which in the judgement of the Investigator, may chemically skew bone marrow. This may include but is not limited to the following:
• •* Cancer
• •* Undergoing chemotherapy radiation,
• •* Bone marrow transplant
• •* Infection at the donor sites
• •* Organ transplant on antirejection meds
• •* Usage of anti-rheumatologic drugs
• •* Chronic steroid usage
• •* Anemia
• •* Myelodysplastic Syndromes
• •Patient presents with arthritis of the knee and may require knee replacement within the next 12 months.