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Exploring the Benefits of Eccentric Training for Aging Adults With Knee Osteoarthritis
This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis. The flywheel device provides resistance throughout the entire movement and gives extra challenge during the muscle-lengthening phase of exercise. This type of training may improve muscle structure, strength, and coordination more effectively than conventional methods. The study's central idea is that better muscle quality and improved coordination will lead to smoother, safer stair movement and reduce the risk of falls. Advanced tools such as ultrasound imaging and motion analysis will be used to measure muscle health and movement patterns in detail. The hypothesis is that individuals with knee osteoarthritis have poorer muscle quality and less coordinated stair-stepping compared to healthy adults, and that performing eccentric overload training will enhance muscle quality, improve movement coordination, and make stair navigation safer and more efficient.
Age
40 - 70 years
Sex
ALL
Healthy Volunteers
Yes
University of Colorado, Denver
Aurora, Colorado, United States
Start Date
August 20, 2025
Primary Completion Date
December 31, 2028
Completion Date
May 31, 2029
Last Updated
February 20, 2026
60
ESTIMATED participants
Eccentric resistance training
OTHER
Lead Sponsor
University of Colorado, Denver
Collaborators
Data Source & Attribution
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