Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions

Inclusion Criteria

• •Patients presenting with a single rooted mandibular premolar tooth with a closed apex and a single patent canal type I in Vertucci's classification (Vertucci et al., 1974).
• •Having a necrotic pulp.
• •A pocket depth measurement of \< 3 mm.
• •Teeth with no previous history of endodontic treatment.
• •Teeth with periapical lesions of endodontic origin having a periapical index score of 4 or 5 (Orstavik et al., 1986)
• •Patients who took antibiotics within the period of three months before the study.
• •Non-restorable teeth.
• •Teeth with periodontal pockets deeper than 4mm, with or without concomitant or combined endo-perio communication
• •Multirooted teeth.
• •Previously initiated or treated teeth.
• •Teeth with root canal calcifications or resorption.
• •Teeth with internal/external root resorption or root fracture.
• •Immune-compromised patients or patients with systemic diseases i.e. (diabetes mellitus, human immunodeficiency virus, leukemia, neutropenia, undergoing chemo- or systemic corticosteroid therapy)
• •Teeth with root curvature of more than 15 degrees.
• •Pregnant women
• •Patients with known sensitivity to the medicaments used in this study.