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Mental Health and Suicidality in Glioblastoma Patients in Germany - a Multicenter Observational Study (SHINE-GLIO Study)
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety symptoms.
Treatment will be provided in accordance with guidelines as part of the study. If a patient decides to participate in the study and have given consent, he/she will undergo a study visit. In addition to a consultation with a physician ("medical history"), this includes a physical examination and the completion of questionnaires (Patient Health Questionnaire-8 to assess depression, Generalized Anxiety Disorder-7 to assess anxiety, Scale of Suicidal Experiences and Behavior to assess suicidality, EORTC-QLQ-30, and EORTC-QLQ BN-20 to assess health-related quality of life, and a short questionnaire on social support for chronic illnesses). If a need for psycho-oncological treatment is identified during the consultation (or during the examination itself) or expressed by the patient, a referral to the relevant specialist department will be arranged (if this has not already been done). Patient data used in the study is taken from the medical record (master data, diagnosis, therapy, MRIs, etc.) and from the study visit.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Charite
Berlin, Germany
University Hospital Knappschaftskrankenhaus Bochum
Bochum, Germany
University Hospital Essen
Essen, Germany
University hospital Hamburg Eppendorf
Hamburg, Germany
University hospital Heidelberg
Heidelberg, Germany
University hospital Muenster
Münster, Germany
Start Date
March 1, 2026
Primary Completion Date
February 28, 2027
Completion Date
December 1, 2027
Last Updated
February 13, 2026
176
ESTIMATED participants
Medical history, physical examination, completing questionnaires, data collection
DIAGNOSTIC_TEST
Lead Sponsor
University Hospital, Essen
Collaborators
NCT07100730
NCT07420543
Data Source & Attribution
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