Effect of Cryotherapy on Anesthetic Success and Pain in Irreversible Pulpitis

Exclusion Criteria

• •Patients who had taken analgesic, anti-inflammatory, or opioid medication within the last 12 hours before treatment,
• •Patients with systemic conditions that may affect pain perception, inflammatory response, or healing,
• •History of antibiotic use within the previous month or requirement for antibiotic prophylaxis,
• •Teeth presenting with clinical or radiographic signs of pulp necrosis or apical periodontitis (Pain on percussion or palpation, presence of sinus tract or swelling, presence of periapical radiolucency),
• •Teeth with root resorption, immature apices, severe coronal destruction preventing proper isolation, or calcified canals,
• •Teeth that had undergone previous endodontic treatment, including pulpotomy or root canal filling,
• •Patients with neurological or psychiatric conditions that could interfere with pain perception or accurate pain reporting,
• •Inability to achieve adequate isolation with a rubberdam.