Presence of self-reported symptoms indicative of cognitive decline or concerns family members/partners indicative of cognitive decline
Capacity to consent
Be fluent in and able to read and write in English and have adequate hearing and visual acuity to complete the required psychometric tests.
You may not be if
Insufficient vision and hearing
Prior diagnosis of ADRD. Prior diagnosis of Alzheimer's disease or related dementia (with or without evidence of pathology), through clinical diagnosis and/or as documented in their medical record
Pre-existing diagnosis of dementia
Incidental findings of brain pathologies on brain MRI, such as cancerous space occupying lesions and clinically significant vascular malformations and recent (within 12 months) macro-infarcts, that are, also exclusionary
Contraindication for Lumbar Puncture
Involvement in interventional research study within 3 months prior to screening
For any other reason, in the opinion of the Investigator, participating in the study is not in the best interest of the patient.