Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Provision of signed and dated informed consent form (ICF)
Male or female adults, aged ≥18 years
Have a BMI at Screening of ≥27.0 kg/m2
Have T2DM for at least 6 months before Screening based on participant reported history or documentation of the disease diagnostic criteria
Have HbA1c value between ≥6.5% (48 mmol/mol) and ≤10.0% (86.0 mmol/mol) at Screening with stable therapy for at least 90 days prior to Screening/Visit 1. T2DM may be treated with:
--Diet and exercise alone or in combination with: Any oral antidiabetic therapy per local labeling EXCEPT DPP-4 inhibitors. Participant may NOT be on GLP-1 agonists or insulin
Participants must be motivated and willing to:
* Self-inject study medication (or be aided by caregiver if needed),
* Perform finger-stick glucose monitoring as required.
Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight.
You may not be if
Female who is breastfeeding, or who is pregnant
Unwilling or unable to follow contraceptive requirements
Diagnosis of Type 1 diabetes, or any other types of diabetes except T2DM.
Severe hypoglycemia and/or hypoglycemia unawareness within the 6 months prior to Screening
Poorly controlled hypertension
Have a prior or planned surgical treatment for obesity (excluding liposuction or abdominoplasty if performed \>1 year prior to screening)
Have taken within 3 months prior to randomization, medications (prescribed or over-the counter) intended to promote weight loss
Are receiving or have received within 3 months prior to screening chronic (\>2 weeks or 14 days) systemic glucocorticoid therapy
