Phuong Duy Nguyen, MD, MS

CONTACT

Lead Sponsor

Hanoi General Hospital (Vietnam)

Age

18 - 40 years

Sex

FEMALE

Healthy Volunteers

No

•Women aged 18-40 years
•Diagnosed with polycystic ovary syndrome (PCOS) according to the modified Rotterdam criteria (2004) (≥2 of 3: oligo/anovulation, hyperandrogenism, or polycystic ovarian morphology on ultrasound)
•Indicated for in vitro fertilization (IVF) due to PCOS alone or PCOS with other infertility factors (e.g., tubal factor, previous failed IUI)
•Eligible for controlled ovarian stimulation for IVF
•Husband/partner with normal sperm parameters or mild to moderate oligoasthenoteratozoospermia (OAT)
•Willing and able to provide written informed consent and comply with study procedures.

•Uterine abnormalities that may impair implantation or pregnancy outcomes, including congenital uterine malformations, large fibroids distorting the uterine cavity, adenomyosis, or severe intrauterine pathology.
•History of major ovarian or uterine surgery affecting ovarian reserve or uterine structure (e.g., ovarian cystectomy, endometriosis surgery, myomectomy, unilateral oophorectomy)
•History of recurrent pregnancy loss (≥3 spontaneous miscarriages)
•Known chromosomal abnormalities in either partner
•Inability to adhere to study protocol or follow-up procedures

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