Age

18–45

Sex

FEMALE

Healthy volunteers

Accepted

Women aged 18 to 45 years
Diagnosis of systemic lupus erythematosus (SLE) according to the EULAR/ACR classification criteria
Remission or low disease activity, defined as SLEDAI-2K ≤ 4
On stable doses of hydroxychloroquine and/or glucocorticoids (≤10 mg/day of prednisone or equivalent) for at least 8 weeks prior to enrollment
Ability and willingness to provide written informed consent
Willingness to maintain usual dietary patterns and physical activity levels throughout the study period

Current use of omega-3 fatty acid supplements or use within the previous 3 months
Pregnancy or lactation
Presence of severe infection, neoplastic disease, or diabetes mellitus
Known allergy or intolerance to fish oil or soybean oil
Any medical condition or circumstance that, in the investigator's opinion, could interfere with study participation or adherence to the protocol

Omega-3 Supplementation in Systemic Lupus Erythematosus