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Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity | Clinical Trials | Clareo Health

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Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity

Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity: A Prospective Randomized Controlled Trial

NCT07389889•Fujian Medical University Union Hospital

View on ClinicalTrials.gov

Summary

1. To compare the precision of robot-guided microwave ablation and CT-guided microwave ablation in the treatment of ground-glass nodules. 2. To evaluate the safety of robot-assisted microwave ablation and CT-guided microwave ablation in the treatment of ground-glass nodules. 3. Explore the application potential of robot navigation microwave ablation technology in the treatment of pulmonary nodules.

Eligibility

Age

18 - 85 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Aged 18 to 85 years
•2. Nodules measuring 3-30mm with ground-glass opacities constituting ≥75% of the lesion
•3. Preoperative clinical evaluation confirming no hilar or mediastinal lymph node metastasis and no distant metastasis
•4. Patients diagnosed as stage IA primary peripheral lung cancer according to the UICC 8th TNM staging system, and with one of the following conditions:
•(i) cannot undergo surgical resection due to poor cardiopulmonary function or advanced age (ii) refusing or unwilling to undergo surgical resection (iii) with newly developed or residual pulmonary nodules after early-stage primary lung cancer surgery (iv) with unilateral lung disease who cannot undergo unilateral surgical resection (v)with multiple primary lung cancers unsuitable for surgical resection
•5. Preoperative ECOG physical status score is 0/1
•6. ASA score is I-III
•7. Patients voluntarily participate in this study and sign the informed consent form

Exclusion Criteria

•1. Smoking cessation duration \<2 weeks
•2. Lesions adjacent to pulmonary artery-vein main trunks
•3. Lesions near the hilum or adjacent to lobar bronchi
•4. Pregnancy or lactation status
•5. Severe mental disorders
•6. History of other malignancies within 5 years
•7. Unstable angina or myocardial infarction within 6 months with coronary angiography showing severe stenosis of major coronary branches
•8. Cerebral infarction or hemorrhage within 6 months
•9. Continuous systemic corticosteroid therapy within 1 month
•10. Patients or their authorized persons who do not wish to comply with the study protocol
+1 more criteria

Key Dates

Start Date

February 1, 2026

Primary Completion Date

February 1, 2028

Completion Date

February 1, 2029

Last Updated

February 5, 2026

Enrollment

116

ESTIMATED participants

Conditions

Pulmonary NodulesGround-glass Opacity

Interventions

Robot

PROCEDURE

CT scan

PROCEDURE

Contacts

Shuliang Zhang

CONTACT

+86 15806024509 670627941@qq.com

Shape-Sensing Robotic-Assisted Bronchoscopy for Diagnosis of Peripheral Pulmonary Nodules in Korea

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 5, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity

Inclusion Criteria

Exclusion Criteria

Shape-Sensing Robotic-Assisted Bronchoscopy for Diagnosis of Peripheral Pulmonary Nodules in Korea

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