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Cardioplegic Protection of the Heart | Clinical Trials | Clareo Health

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Cardioplegic Protection of the Heart

The Type of Cardioplegia and Cardiometabolic Impact - a Prospective Randomized Trial in Patients Undergoing CABG

NCT07386990•Region Skane

Summary

This study seek to compare two different solutions used to protect the heart during cardiac surgery. 40 adult patients planned for coronary artery bypass surgery with cardiopulmonary bypass machine assistance will be included in the study. Blood samples from the first 48 hours after surgery will be analyzed together with physical data, x-ray-results, ecg and general outcome after surgery.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients scheduled for non urgent, single procedure coronary artery bypass grafting surgery at Skåne university hospital in Lund Sweden

Exclusion Criteria

•Moderate and severe aortic valve insufficiency.
•Type 1 diabetes.
•Renal insufficiency (=estimated glomerular filtration rate \<60 mL/min/1,73m2)
•Not communicating in Swedish language.
•Previous cardiac surgery.

Locations (1)

Cardiothoracic surgery department, Skåne university hospital, Lund

Lund, Sweden

Key Dates

Start Date

June 15, 2021

Primary Completion Date

November 18, 2021

Completion Date

April 29, 2025

Last Updated

February 12, 2026

Enrollment

ACTUAL participants

Conditions

Coronary Artery Bypass Graft (CABG)CardioplegiaCardiopulmonary BypassPerioperative Myocardial Injury

Interventions

Modified Buckberg cardioplegic solution

DRUG

Modified St Thomas´ cardioplegic solution

DRUG

Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy

NCT06984276

UltrasoundPectoral Nerve Block+5 more

View study

RECRUITINGNA

Effect of Low Tidal Volume Ventilation on Postoperative Delirium

NCT06752421

Postoperative Delirium (POD)Cardiopulmonary Bypass+2 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 12, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Cardioplegic Protection of the Heart

Inclusion Criteria

Exclusion Criteria

Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy

Effect of Low Tidal Volume Ventilation on Postoperative Delirium

Amobarbital and Cardiopulmonary Bypass

Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery

Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surgery (PANDA IV)

Influence of Lung Volume Optimization Maneuver in Ventilated Children on Cardiac Output and Lung Compliance in Children With Congenital Heart Disease Undergoing Surgical Repair