Efficacy and Safety of Anricofen Combined With Ciprofol for Deep Sedation in Elderly Patients Undergoing ERCP

Exclusion Criteria

• •1. Severe neurological disorders (acute stroke, uncontrolled seizures, epilepsy).
• •2. Psychiatric disorders or cognitive impairment (Mini-Mental State Examination score \<24).
• •3. Uncontrolled hypertension (preoperative blood pressure ≥180/110 mmHg) or hypotension (\<90/60 mmHg).
• •4. Severe cardiac disease: sinus bradycardia, sick sinus syndrome, unstable angina, or myocardial infarction within the past 3 months.
• •5. Severe hepatic or renal dysfunction.
• •6. Difficult airway or severe respiratory disease.
• •7. Achalasia.
• •8. Known allergy to anricofen, sufentanil, ciprofol, or other study medications.
• •9. Use of opioid analgesics or sedatives within 7 days prior to surgery.
• •10. Preoperative pulse oxygen saturation (SpO₂) \<90% on room air.
• •11. Pregnancy or lactation.
• •12. Participation in any other drug clinical trial within the past 3 months.
• •13. Refusal to participate in the study.
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