Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne

Exclusion Criteria

• •1. Have used antibiotics within 1 month before the study start.
• •2. Have used systemic retinoid therapy within 3 months before the study start.
• •3. Have undergone any other acne treatment within 1 month before the study start.
• •4. Have any other condition that the investigator considers would make participation unsuitable (e.g., deemed unreliable, non-compliant, or unable to comprehend the study assessments).