A Cohort Study of the Efficacy and Safety of Biologics in Patients With ABPA

Inclusion Criteria

• •1. Meet the diagnostic criteria of allergic bronchopulmonary aspergillosis, according to the ISHAM guidelines for the diagnosis and treatment of allergic bronchopulmonary aspergillosis (2024 revision).
• •2. The underlying disease was bronchial asthma, and it was severe bronchial asthma.
• •3. Have had an acute asthma attack in the past year. Acute exacerbation of asthma is defined as the sudden onset of wheezing, shortness of breath, cough, chest tightness and other symptoms beyond the definition of uncontrolled asthma, or the aggravation of the original symptoms, and is characterized by decreased expiratory flow, often induced by exposure to allergens, irritants or respiratory tract infection.
• •4. Blood eosinophil count ≥150 cells /μL.
• •5. Age ≥ 18 years old.