A confirmed diagnosis of multiple sclerosis (MS) established by a neurologist,
Not being in a relapse phase and having no MS relapse within the past 6 months,
Aged between 18 and 60 years,
Disease severity within an Expanded Disability Status Scale (EDSS) range of 1-5 (mild to moderate functional impairment),
Visual, auditory, and vestibular functions sufficient to tolerate mixed reality-based applications,
Adequate cognitive capacity to actively participate in the study (e.g., Mini-Mental State Examination score ≥ 24),
Ability to read, understand, and follow instructions in Turkish,
Willingness to participate voluntarily in the study and provision of written informed consent.
You may not be if
Having experienced a multiple sclerosis relapse or undergone a change in MS-related treatment within the past 6 months,
Presence of severe musculoskeletal disorders (e.g., fracture, arthritis, advanced osteoarthritis, muscle tear) that may interfere with test performance,
Presence of severe cardiopulmonary disease (e.g., uncontrolled hypertension, heart failure, chronic obstructive pulmonary disease) or any medical condition that may pose a risk during exercise testing,
Risk of loss of balance or spatial disorientation in the mixed reality environment due to visual, vestibular, or auditory impairments,
Inability to perform functional tests due to severe spasticity, contractures, or orthopedic deformities,
History of epilepsy, migraine, or other neurological conditions that contraindicate the use of mixed reality or virtual reality devices,
Inability to understand test instructions due to cognitive impairment or severe mental health disorders (e.g., dementia, major depression, psychotic disorders),
Experiencing dizziness, nausea, or virtual reality-related symptoms (VR sickness) during testing,
Insufficient motivation or poor compliance that may hinder participation in the study.
Clareo Health | Validity and Reliability of Mixed Reality-Based Mobility Tests in Multiple Sclerosis
