Unresectable, locally advanced, or metastatic solid tumor (other than CCA).
Documented FGFR2 gene fusion or rearrangement per local testing of blood and/or tumor.
Patient must have measurable disease per RECIST v1.1• Patient has ECOG performance status of 0-1.
Previously (\>30 days) treated with ≥1 line of systemic therapy including chemotherapy (e.g., gemcitabine/cisplatin), immunotherapy, radiation therapy, or other approved therapies.
Subject has not received prior treatment with an FGFRi.
You may not be if
An uncontrolled comorbidity.
Patient does not have adequate organ function (defined in protocol).
Patient has active infection, including human immunodeficiency virus (HIV), hepatitis B virus (HBV), and/or hepatitis C virus (HCV) (defined in protocol). Patients with well-controlled HBV are eligible (defined in protocol).
QT interval corrected using Fridericia's formula (QTcF) \> 480 msec or history of prolonged QT syndrome, Torsades de pointes or familial history of prolonged QT syndrome.
