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Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization | Clinical Trials | Clareo Health

COMPLETEDNA

Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization

A Randomized Controlled Clinical Trial Comparing Cyanoacrylate and Sutures for Free Gingival Graft Stabilization

NCT07359300•Yeditepe University

Summary

This randomized controlled clinical trial evaluated the effectiveness of butyl-cyanoacrylate tissue adhesive compared with conventional sutures for stabilization of free gingival grafts. Twenty-four patients with insufficient keratinized tissue were randomly assigned to either cyanoacrylate or suture stabilization following free gingival graft surgery. Clinical parameters, graft dimensional changes, patient-reported postoperative discomfort, and operative time were assessed over a 6-month follow-up period.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Adults aged 18 years or older
•Presence of ≤1 mm of keratinized tissue and/or Miller Class I gingival recession ≤2 mm affecting one to four mandibular anterior teeth
•Vital teeth in the surgical area
•Good oral hygiene following initial periodontal therapy (full-mouth plaque score and full-mouth bleeding score ≤20%)
•Ability to understand the study procedures and provide written informed consent

Exclusion Criteria

•Current smokers
•Pregnancy or lactation
•Use of systemic antibiotics within the previous 6 months
•History of periodontal surgery in the study area
•Ongoing orthodontic treatment
•Systemic conditions that could affect periodontal healing

Locations (1)

Yeditepe University

Istanbul, Turkey (Türkiye)

Key Dates

Start Date

June 1, 2019

Primary Completion Date

August 1, 2021

Completion Date

August 1, 2021

Last Updated

January 22, 2026

Enrollment

ACTUAL participants

Conditions

Insufficient Keratinized TissueGingival RecessionMucogingival Defects

Interventions

Free Gingival Graft Stabilization With Butyl-Cyanoacrylate

PROCEDURE

Free Gingival Graft Stabilization With Sutures

PROCEDURE

A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth

NCT07437417

Gingival RecessionConnective Tissue Defect

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RECRUITINGNA

Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT

NCT07440303

Lack of Keratinized GingivaMucogingival Deformity - Insufficient Keratinized Tissue

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 22, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization

Inclusion Criteria

Exclusion Criteria

A Novel Volume Stable Matrix for Gingival Recession Coverage at Teeth

Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT

Changes in Soft Tissue Thickness Following Multiple Coronally Advanced Tunnel (MCAT) vs Vestibular Incision Subperiosteal Tunnel Access (VISTA)

Comparing TCAF and MTUN With Soft Tissue Grafting for Treating Single Recessions in the Premandible

NovoMatrix in Gingival Recession Coverage: Case Series

Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects