Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in ASCVD (HEARTWISE-ASCVD)

Inclusion Criteria

• •Non-gated chest CT performed within the prior 2 years within the health system
• •Active health system engagement with an affiliated clinician eligible for notification, defined as ≥1 clinical visit within the prior 2 years AND at least one of the following:
• •1. Active enrollment in the site's integrated healthcare plan (e.g., Kaiser Permanente Northern California), OR
• •2. LDL-C measured within the health system within the prior 2 years, OR
• •3. Outpatient cardiovascular medication prescription within the prior year
• •Meets one of the following clinical criteria:
• •1. Clinical ASCVD diagnosis (coronary artery disease, peripheral arterial disease, or ischemic cerebrovascular disease) AND AI-detected CAC \>0 on non-gated chest CT, OR
• •2. No ASCVD diagnosis AND AI-detected CAC ≥100
• •Suboptimal LDL-C control, defined as either: Last LDL-C ≥70 mg/dL in the last 2 years, OR No LDL-C measurement in the last 2 years
• •Note: Site-level variations and additional refinements may occur based on local stakeholder input and patient population identification.