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Effect of Different Root Canal Disinfection Procedures on Postoperative Pain | Clinical Trials | Clareo Health

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Effect of Different Root Canal Disinfection Procedures on Postoperative Pain

Effect of Different Root Canal Disinfection Procedures on Postoperative Pain: A One-Week Follow-Up Clinical Study

NCT07355816•Cumhuriyet University

Summary

This clinical study evaluated the effects of different root canal disinfection procedures on postoperative pain. Patients requiring root canal treatment received one of several disinfection methods. Postoperative pain was assessed at 6,24, 48, 72 hours and on the 7th day using a standard pain scale. The aim of the study was to identify which method resulted in the least discomfort. Participation involved a single treatment session and short-term follow-up for pain measurement.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Systemically healthy individuals between the ages of 18 and 65,
•Adequate mouth opening,
•Asymptomatic devitaled mandibular premolar with a single root and single canal,
•Negative response to cold and electric pulp tests and no bleeding at the pulp chamber opening,
•Able to provide rubber dam isolation,
•Presence of opposing teeth.

Exclusion Criteria

•Presence of mental or psychiatric disorders,
•Allergic diseases,
•Use of painkillers within 12 hours or antibiotics within 1 week before the procedure,
•Swelling, palpation/percussion pain, or sinus tract before treatment,
•Presence of a periodontal pocket greater than 3 mm in diameter on the involved tooth,
•Presence of a periapical radiolucency greater than 5 mm in diameter associated with the involved tooth,
•Initiation of root canal treatment,
•Irreparable material loss, root fracture, or crack,
•Severe mobility,
•Open apex,
+5 more criteria

Locations (1)

Faculty of Dentistry, Cumhuriyet University, Sivas

Sivas, Turkey (Türkiye)

Key Dates

Start Date

June 13, 2023

Primary Completion Date

November 11, 2024

Completion Date

November 11, 2024

Last Updated

January 21, 2026

Enrollment

ACTUAL participants

Conditions

Pain, Postoperative

Interventions

Conventional Needle Irrigation

PROCEDURE

Passive Ultrasonic Irrigation

PROCEDURE

Sonic Irrigation

PROCEDURE

KTP Laser Disinfection

PROCEDURE

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 21, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effect of Different Root Canal Disinfection Procedures on Postoperative Pain

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