A Study of Cizutamig for Patients With Ulcerative Colitis

Inclusion Criteria

• •1. 18-75 years of age at the time of signing the informed consent form (ICF)
• •2. Have an established diagnosis of UC
• •3. Have current evidence of active moderate to severe UC.
• •4. Have current evidence of UC extending proximal to the rectum
• •5. Demonstrated intolerance or inadequate response to ≥ 1 biologic and/or other advanced therapies
• •6. Stable use of any of the following background therapy (alone or in combination) up to Day 1
• •7. Have documentation of:
• •1. A surveillance colonoscopy (performed according to local standards) within 12 months of or during Screening, for patients with pancolitis of \> 8 years duration, left-sided colitis of \> 12 years duration, or primary sclerosing cholangitis; OR