Patients diagnosed as SLE according toSLICC 2012Classification Criteria\[13\] :
A. Patients presented with typical lupus presentation:
1. age of onset (20-50)
2. common initial manifestations as constitutional manifestations,arthritis, mucocutaneousmanifestationslike malar rash, photosensitivity and hair falling.
3. patients with ANA positive.
B. Patients presented with atypical lupus presentation:
1. any clinical presentation not belonging to classic common SLE onset features, including but not limited to:
* Fever of unknown origin (FUO) as sole initial presentation
* Thrombotic events
* Generalized lymphadenopathy.
2. Patients with dominant organ affection.
3. patients with late onset SLE.
4. patients with ANA negative SLE. C.Patients who can provide informed consent.
You may not be if
1. Patients whose initial symptoms are clearly attributable to infection, sepsis or another non-SLE condition.
2. Patients with chronic pre-existing diseases that may mimic or obscure the initial SLE presentation (e.g. primary epilepsy, primary pulmonary hypertension, chronic liver or GI disease).
3. Patients in whom onset features cannot be reliably classified as typical or atypical due to mixed or unclear presentation.
\-
Clareo Health | It is an Observational Study That Compare Prognosis of Typical and Atypical Systemic Lupus Erythematosus Presentation
