Loading clinical trials...

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management | Clinical Trials | Clareo Health

RECRUITINGNA

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management.

NCT07346976•The Fourth Affiliated Hospital of Zhejiang University School of Medicine

View on ClinicalTrials.gov

Summary

The objective of this study is to ascertain the diagnostic threshold of end-tidal carbon monoxide (ETCOc, adjusted for ambient CO levels) within the first three days postpartum, stratified by neonatal age at birth. Additionally, the study aims to evaluate the concordance of the risk range of ETCOc, as measured by non-dispersive infrared spectroscopy, with existing literature, and to assess the reliability of this technology in the management of neonatal hyperbilirubinemia.

Eligibility

Age

0 - 0 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Newborns with gestational age of ≥ 37 weeks and birth weight of ≥ 2.5 kg;
•2. Newborns delivered by either vaginal delivery or cesarean section and with hospital stay of ≥ 3 days.

Exclusion Criteria

•1. History of second-hand smoke exposure within 24 hours
•2. Parents smoke or are exposed to second-hand smoke.

Locations (1)

4th Affiliated Hospital, School of Medicine, Zhejiang University

Yiwu, Zhejiang, China

Key Dates

Start Date

December 5, 2025

Primary Completion Date

July 1, 2026

Completion Date

July 1, 2027

Last Updated

January 16, 2026

Enrollment

100

ESTIMATED participants

Conditions

Neonatal Hyperbilirubinemia

Interventions

Erythrocyte Life Span Tester

DEVICE

Contacts

Yixiang Wu

CONTACT

+8613600643385 laibujilene@163.com

Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia

NCT06517862

Neonatal Hyperbilirubinemia

View study

ACTIVE_NOT_RECRUITING

Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns

NCT06687746

Jaundice, NeonatalNeonatal Diseases and Abnormalities+3 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 16, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management

Inclusion Criteria

Exclusion Criteria

Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia

Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns

Wireless Irradiance SEnsors During Neonatal Phototherapy

Transcutaneous Bilirubinometry and Phototherapy

Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants

Reverse Phototherapy With Super Light-emitting Diode(Super-LED) for Hyperbilirubinemia in Term and Late Preterm Infants