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Efficacy of Intravenous Vitamin C Versus Placebo on Estimated Blood Loss in Total Abdominal Hysterectomy
Intervention Group: Received two 1 gm doses of Vitamin C intravenously (IV). first Dose: At midnight on the day of surgery. Second Dose: Immediately after the surgical incision. Control Group: Received two doses of a normal saline intravenously (IV) at the exact same times. The primary outcome was to compare intraoperative blood loss between patients who received intravenous Vitamin C and those who did not, following an abdominal hysterectomy under general anesthesia. Intraoperative estimated blood loss (EBL) was meticulously quantified by weighing surgical gauze and measuring suction canister volumes. The secondary outcomes were to evaluate the potential benefits of Vitamin C administration, including: * Reduction in the decline of hematocrit levels after surgery. * Reduction of the length of hospital stay
Age
20 - No limit years
Sex
FEMALE
Healthy Volunteers
No
Queen Savang Vadhana Memorial hospital
Si Racha, Changwat Chon Buri, Thailand
Start Date
September 1, 2024
Primary Completion Date
July 31, 2025
Completion Date
July 31, 2026
Last Updated
January 13, 2026
40
ESTIMATED participants
Vitamin C (Ascorbic Acid)
DIETARY_SUPPLEMENT
Lead Sponsor
Queen Savang Vadhana Memorial Hospital, Thailand
NCT06765512
NCT06524934
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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View ClinicalTrials.gov Terms and ConditionsNCT06114758